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DISCOVERY OF NEW HORMONE MEDIATORS IN OBESITY

 Two new neuropeptides, called Orexin A and Orexin B (OX-1R and OX-2R), which directly influence obesity, have recently been discovered in the lateral part of the hypothalamus, which is directly linked to the center of hunger,thus curbing the appetite.

 This is currently under study and we should have results in humans shortly.

A COHERENT LINK WAS FOUND BETWEEN THE ATTITUDE OF PATIENTS AND THEIR NEUROENDOCRINE CHARACTERISTICS IN NOCTURNAL EATERS'SYNDROME.

 The nocturnal eater syndrome is characterized by:

  • Morning Anorexia

  • Compulsive nocturnal eating and

  • Insomnia

 In a study recently published in the Journal of the American Medical Association (JAMA), it was found that the hormone levels of melatonine, cortisol and leptin, are very characteristic in this syndrome, revealing that these patients presented low nocturnal levels of melatonine and leptin, whereas the levels of cortisol were found to be high. Therefore it is proven that an identical pattern in patients with this syndrome DOES exist.

EXERCISE HAS SHOWN AN INFLUENCE IN THE TREATMENT OF OBESITY, REGARDLESS OF THE GENETIC CHARGE:

 In a study recently published in the Annals of Internal Medicine, a survey was taken of 1,000 twins (identical and non-identical) ages between 28 and 48 years, in Sydney, Australia.

 It was revealed that while the diet did NOT influence the reduction program greatly, in several patients with a genetic predisposition to obesity, exercise DID have a great influence in the reduction program.


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Medical supervision by Dr. Arieh Goldberg Kalik.
Bariatric physician, certified medical nutrition specialist. Certificate # 1010084

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